Aqemia

Aqemia is a next-generation pharmatech company founded in 2019 as a deeptech spinoff from École Normale Supérieure that revolutionizes drug discovery by combining quantum-inspired physics algorithms with generative AI, enabling molecule exploration 10,000 times faster than conventional methods without requiring experimental training data. In 2024, Aqemia raised €60 million in Series A funding led by Cathay Innovation, bringing total funding to over €100 million, to prepare for clinical trials and fuel international expansion with a new London office opening in January 2025. The company currently has three cancer-targeting drug candidates undergoing preclinical animal testing, having progressed to this stage in under two years with expectations to move into clinical trials by 2025. Aqemia’s quantum-inspired algorithms simulate molecular behavior at unprecedented accuracy and speed, training AI models on physical laws governing molecular structures. Major partnerships include a $140 million collaboration with Sanofi and agreements with Servier and Johnson & Johnson to accelerate oncology drug development through physics-based molecular design.

Pfizer

Pfizer investigates quantum computing applications for pharmaceutical research and drug discovery, exploring quantum algorithms for molecular modeling, drug design optimization, and clinical trial analytics that could accelerate the development of new vaccines and therapeutic treatments, collaborating with quantum computing companies and academic institutions to leverage quantum simulation capabilities for understanding complex biological systems, protein interactions, and drug mechanisms of action, contributing to the pharmaceutical industry’s adoption of quantum technologies to enhance research productivity, reduce development costs, and improve patient outcomes through more effective drug discovery and personalized medicine approaches.

POLARISqb

POLARISqb is a US quantum biotechnology company founded in 2020 that applies quantum computing and quantum-inspired algorithms to accelerate drug discovery and development, using quantum molecular simulation and optimization techniques to identify novel drug candidates and optimize molecular properties more efficiently than classical computational methods, focusing on leveraging quantum advantage for pharmaceutical applications including drug design, molecular modeling, and therapeutic target identification to reduce drug development timelines and costs.

Qubit Pharmaceuticals

Qubit Pharmaceuticals is a Paris and Boston-based quantum-enhanced drug discovery company founded in 2020 that accelerates pharmaceutical research using hybrid quantum-classical computing through their Atlas platform, achieving molecular simulations 100,000 times faster than traditional methods while reducing drug candidate screening from 5,000 to 200 compounds, with breakthrough technologies including the Hyperion-1 quantum emulator simulating 40 qubits and the FeNNix-Bio1 quantum AI foundation model developed with Sorbonne University, operating one of France’s largest GPU supercomputers and advancing 7 therapeutic programs particularly in oncology and inflammation.

Roche

Roche explores quantum computing applications for pharmaceutical research and drug discovery, investigating quantum algorithms for molecular simulation, protein folding prediction, and drug-target interaction modeling that could accelerate the development of new medicines and personalized therapies, collaborating with quantum computing companies and research institutions to leverage quantum advantages in computational chemistry, clinical trial optimization, and biomarker discovery, exploring how quantum machine learning and quantum simulation could enhance pharmaceutical research capabilities and reduce drug development timelines while improving therapeutic outcomes for patients across oncology, immunology, and other therapeutic areas.

Rolls-Royce

Rolls-Royce explores quantum computing applications for aerospace and energy sectors, investigating quantum algorithms for engine design optimization, materials simulation, supply chain management, and predictive maintenance to enhance efficiency and performance in aviation and power generation systems.

Company Information

• Founded: 2021
• Country: United Kingdom
• Website: https://rolls-royce.com
• Categories: applications

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Shell

Shell investigates quantum computing applications for energy optimization and oil & gas operations, exploring quantum algorithms for reservoir simulation, molecular modeling for catalyst design, logistics optimization, and energy trading to improve efficiency and reduce environmental impact in energy production and distribution.

Company Information

• Founded: 2020
• Country: Netherlands
• Website: https://shell.com
• Categories: applications

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TotalEnergies

TotalEnergies explores quantum computing applications for energy sector optimization and sustainability initiatives, investigating quantum algorithms for renewable energy grid optimization, carbon capture simulation, oil reservoir modeling, and energy trading strategies, collaborating with quantum computing companies and research institutions to develop quantum solutions for complex energy challenges including molecular simulation for battery materials, catalyst design for cleaner energy production, and optimization of energy distribution networks, contributing to the energy industry’s digital transformation through quantum-enhanced modeling and optimization capabilities that could improve energy efficiency and accelerate the transition to sustainable energy systems.

Volkswagen

Volkswagen is a German automotive company that pioneered quantum computing applications in the automotive industry, developing quantum algorithms for traffic flow optimization, route optimization, and autonomous vehicle coordination using D-Wave quantum annealing systems to optimize taxi routing in major cities, investigating quantum machine learning for predictive maintenance, battery optimization for electric vehicles, and supply chain management, collaborating with quantum computing companies to explore quantum advantages in manufacturing optimization, materials simulation for vehicle design, and logistics coordination across their global automotive production and distribution network.